NEWS DESK
Ambulatory BP Predicts Renal and CV Events
In a study of 436 patients with chronic kidney disease not on dialysis (mean age 65.1 years), ambulatory blood pressure (BP) measurements showed risk of both renal and cardiovascular (CV) events to be highest when daytime systolic BP was 135 mm Hg or higher, when diastolic BP was in the highest quintile, and when nighttime systolic BP was 124 mm Hg or higher. Nighttime diastolic BP of 70 mm Hg or higher was a predictor of CV events and end-stage renal disease. Office BP measurement were not predictive of CV or renal events, researchers reported in Archives of Internal Medicine (2011;171:1090-1098).
Persistent Hematuria in Kids Portends ESRD
End-stage renal disease (ESRD) is more likely to develop in adolescents and young adults with persistent microscopic hematuria, according to a report in the Journal of the American Medical Association (2011;306:729-736).
Over nearly 22 years of follow-up, treated ESRD developed in 26 of 3,690 (0.70%) persons aged 16 through 25 years who had been diagnosed with persistent asymptomatic isolated microscopic hematuria at baseline compared with 539 of 1,199,936 patients (0.045%) without such a diagnosis. In adjusted analyses, ESRD was 18.5 times more likely to develop in subjects with hematuria. The authors noted, however, that the incidence and absolute risk of ESRD remain quite low.
Source: Nephrology and Cardiology News Portal/2011/September
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